Parkinson's Health - Continued - Page 2

The particles we're interested in is ultra fine particles. These are less than a tenth of a micro meter and less in diameter is because of where they might end up in the body. These are very very fine particles that we can inhale into our lungs, but they can also be taken up by the lung and can get into the blood stream and circulate around our body. And when inside the nose they can move up to the structure of the brain through that mechanism as well. It does not matter what these particles are made of. Its the fact they are so small that makes them a problem. Its what enables them to get into the brain. Our research shows pretty conclusively that there is a gradient risk for developing dementia as one lives closer to a major roadway, but for two other disease we looked at,  Parkinson's disease and multiple sclerosis, there was no change in risk that varied with how close you were living to the roadway. People who lived within 50 metres of a major road way and compared those with people who lived greater than 300 metres away, and we found a very clear gradient risk the closer you got to the roads. They were 7% more likely to develop dementia than people who lived farer away from the roadway. Once you were 200 metres away from the roadway, we couldn't find any increase in risk. Professor Ray. Chef environment and occupational health. BBC World Service. Crowd Science.

A new trial drug for 'Parkinson's disease'. You can't really treat it in the most common sense in trying to stop the disease. All you can do is try to manage the symptoms. There are drugs out there that will boost dopamine levels, to try and combat some of those movement disorders. What you never do in Parkinson's disease is slow the pace of the disease itself. This new trial is to try to stop those brain cells from dying in the first place. In a year long trial, people who we're getting normal therapy predictable got worse. The people, who were taking the 'diabetes' drug didn't get worse, their symptoms stayed stable over the year. Now a lot of medical research is looking at this concept of re-,purposing, are there already drugs out there for some conditions that might help in something else.  James Gallagher. BBC World Service Health Check.

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